From the McGill Pharmacoepidemiology Research Unit, Jewish General Hospital, Departments of Epidemiology and Biostatistics and of Medicine, McGill University, Montreal, QC, Canada.
A new analysis of the Womens Health Initiative (WHI) study has found that, among recently menopausal women, estrogen-plus-progestin hormone-replacement therapy (HRT) slightly increased the risk of coronary heart disease within the first few years of use. But the increase was not statistically significant.
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